|
KMID : 0363019890190010001
|
|
Journal of Korean Academy of Periodontology
1989 Volume.19 No. 1 p.1 ~ p.8
|
|
|
The comparative study of immunosuppressive drugs on the periodontal condition in Renal transplant Patients
|
|
Lee Dong-Ho
Choi Sang-Mook
|
|
|
Abstract
|
|
|
|
The periodontal condition of 22 patients on cyclosporin therapy and 12 patients on azathioprine therapy after renal transplantation was compared with that of 10 prospective renal transplant patients. Significant correlation was observed for plaque scores on gingival inflammation in renal transplant group, but not in chronic renal failure group (p < 0.01). Patients on azathioprine therapy had significantly more gingival inflammation and pocket depth greater than 3 mm than those of cyclosporin and chronic renal failure group (p < 0.01). Gingival hyperplasia was observed in 13 of 22 patients on cyclosporin therapy and one patient on azathioprine therapy. Gingival hyperplasia associated with cyclosporin therapy occurred more in the anterior than in the posterior segments, although the degree was more severe in the posterior segments (p< 0.05). A significant correlation (r-0.557, p<0.05) was observed between the duration of cyclosporin therapy and the increase in gingival hyperplasia, but not the duration of immunosuppressive therapy and the severity of gingival inflammation or pocket formation.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|